MUTATION ANALYSIS OF THE NRXN1 GENE IN AUTISM SPECTRUM DISORDERS

Mutation analysis of the NRXN1 gene in autism spectrum disorders

The aim of this study was to identify the sequence mutations in the Neurexin 1 (NRXN1) gene that has been considered Cable Pin as one of the strong candidate genes.A total of 30 children and adolescents (aged 3-18) with non syndromic autism were enrolled this study.Sequencing of the coding exons and the exon-intron boundaries of the NRXN1 gene was

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Insights into the Roles of B Cells in Patients with Sepsis

Sepsis is a life-threatening yet common disease, still posing high mortality worldwide.Sepsis-related deaths Feverfew primarily occur during immunosuppression; the disease can hamper the numbers and function of B cells, which mediate innate and adaptive immune responses to maintain immune homeostasis.Dysfunction of B cells, along with aggravated im

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Consequences of group III/IV afferent feedback and respiratory muscle work on exercise tolerance in heart failure with reduced ejection fraction

Abstract Exercise intolerance and exertional dyspnoea are the cardinal symptoms of heart failure with Cable Pin reduced ejection fraction (HFrEF).In HFrEF, abnormal autonomic and cardiopulmonary responses arising from locomotor muscle group III/IV afferent feedback is one of the primary mechanisms contributing to exercise intolerance.HFrEF patients

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Technical Evaluation of Soft Mist Inhaler Use in Patients with Chronic Obstructive Pulmonary Disease: A Cross-Sectional Study

Wei Zhang,1,* Lili Xu,1,* Shen Gao,2 Nan Ding,2 Ping Shu,1 Zhuo Wang,2 Yuping Li1 1Department of Pharmacy, Shanghai Pulmonary Hospital, Tongji University School of Medicine, Shanghai 200433, People’s Republic of China; 2Department of Pharmacy, Changhai Hospital Affiliated to The Second Military Medical University, Shanghai 200433, People&rsqu

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